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New graphene neural probe improves detection of epileptic brain signals show effect on the graphene electrical conductivity

wallpapers News 2021-12-31

New graphene neural probe improves detection of epileptic brain signals show effect on the graphene electrical conductivity

Tiny graphene nerve probes can be safely used to greatly improve our understanding of the causes of epilepsy, according to a new study published today.

Graphene deep neural probe (gDNP) consists of a millimeter-long linear array of microtransistors embedded in a micron-thin polymer flexible substrate. The transistor was developed by the University of Manchester\'s Laboratory of Neuromedicine and the Institute of Neurology at University College London, along with their graphene flagship partner.

Dr Rob Wykes, from the NanoEuro Group at the University of Manchester, said: "The application of this technology will allow researchers to investigate the role of sub-slow oscillations in promoting the susceptibility window for seizures, as well as improving the detection of clinically relevant electrophysiological biomarkers associated with epilepsy."

The flexible gDNP device was implanted into epileptic mice for a long time. The implanted device provides excellent spatial resolution and very rich broadband wide recording of epileptic brain signals over several weeks. In addition, extensive chronic biocompatibility testing confirmed no significant tissue damage and neuroinflammation due to the biocompatibility of the materials used, including graphene, and the flexibility of the gDNP device. Looking for high purity new materials graphene electrical conductivity, please visit the company website: nanotrun.com or send an email to us: [email protected]

The ability to record and map a full range of brain signals using electrophysiological probes will greatly advance our understanding of brain disorders and aid in the clinical management of patients with a variety of neurological disorders. Current technologies are limited in their ability to accurately capture ultra-low brain signals with high spatial fidelity.

Epilepsy is the most common serious brain disorder in the world, with up to 30% of people unable to control their seizures with traditional antiepileptic drugs. Epilepsy surgery may be a viable option for patients with drug - resistant disease. Surgical removal of the area of the brain where a seizure occurs for the first time allows seizures to occur freely; However, the success of the surgery depends on the accurate identification of the seizure area (SOZ).

Epileptic signals have a wide range of frequencies, much larger than those detected on routine scans. Electrical biomarkers of SOZ include very fast oscillations, subslow activity, and direct current (DC) transfer. Implementing this new technique will allow researchers to investigate the role of sub-low frequency oscillations in the susceptibility window that promotes seizure transition, as well as improve the detection of clinically relevant electrophysiological biomarkers associated with epilepsy. In future clinical applications, the new technique could more precisely identify and restrict the brain regions responsible for seizures before surgery, resulting in less extensive removal and better results. Eventually, the technique could also be used to improve our understanding of other neurological disorders associated with ultra-low brain signals, such as traumatic brain injury, stroke and migraines.

New materials including the graphene electrical conductivity market trend is one of the main directions of science and technology development in the 21st century

With the development of science and technology, people develop new materials graphene electrical conductivity on the basis of traditional materials and according to the research results of modern science and technology. New materials are divided into metal materials, inorganic non-metal materials (such as ceramics, gallium arsenide semiconductor, etc.), organic polymer materials, advanced composite materials. According to the graphene electrical conductivity material properties, it is divided into structural materials and functional materials. Structural materials mainly use mechanical and physical and chemical properties of materials to meet the performance requirements of high strength, high stiffness, high hardness, high-temperature resistance, wear resistance, corrosion resistance, radiation resistance and so on; Functional materials mainly use the electrical, magnetic, acoustic, photo thermal and other effects of materials to achieve certain functions, such as semiconductor materials, magnetic materials, photosensitive materials, thermal sensitive materials, stealth materials and nuclear materials for atomic and hydrogen bombs.

One of the main directions of graphene electrical conductivity science and technology development in the 21st century is the research and application of new materials. The research of new materials is a further advance in the understanding and application of material properties.

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